Anti-Macaque pan-species IgG [1B3]

Absolute Antibody

Anti-Macaque pan-species IgG [1B3]

9

This antibody reacts with rhesus macaque IgG1 and IgG3, as well a cynomolgus monkey, pigtailed macaque and baboon IgG. It has minimal reactivity with human, mangabey, vervet, chimpanzee, or marmoset IgG.

This anti-macaque antibody has been used in ELISA analysis to detect rhesus anti-mouse antibodies in serum samples (Page et al, 2012). As this antibody is able to distinguish between human and macaque IgG, it has also been used in ELISA analysis to detect macaque antibodies raised against intravenously-administered human HIV broadly neutralising antibodies (Rosenberg et al, 2015). Additionally, it has been used in flow cytometric analysis to confirm the clearance of intravenously-administered anti-CD4 depleting antibody from the plasma of rhesus macaques (Mudd et al, 2011).

Flow Cytometry, ELISA

Research Use Only

Monoclonal

1B3

Rabbit

IgG

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Monkey, Primate

-20°C,2°C to 8°C

12352203