Anti-mammalian sTnI [6G1]

Absolute Antibody

Anti-mammalian sTnI [6G1]

9

This antibody is specific for mammalian skeletal Troponin I (sTnI) and can cross-react with skeletal Troponin C (sTnC).

This antibody was originally reported to react with equine (horse) Troponin I (TnI) as determined by ELISA (US7297500B2). Later, it was shown through WB to bind mammalian skeletal TNI (sTnI), specifically bovine (cow) and porcine (pig), where it was shown to be immunoreactive to both sTnI and skeletal Troponin C (sTnC). However, sTnC was not detected by this antibody following extraction using urea and betaME supplemented extraction buffer, indicating that their addition leads to the destruction of the antibodys epitope on sTnC. In a sandwich ELISA, it was determined that this antibody detects heated bovine, cervine (deer), equine, ovine (sheep), and porcine samples (Jiang et al., 2020; DOI: 10.1016/j.foodcont.2019.107045).

Western Blot, ELISA

Research Use Only

Monoclonal

6G1

Rabbit

IgG

Bovine, Deer, Equine, Porcine, Sheep

-20°C,2°C to 8°C

12352203