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anti-MBNL1 antibody [1H1]

ARG10721
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityChicken, Human
TargetMBNL1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-MBNL1 antibody [1H1]
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1H1
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4154
  • Target name
    MBNL1
  • Target description
    muscleblind like splicing regulator 1
  • Target synonyms
    EXP; MBNL; muscleblind-like; muscleblind-like protein 1; triplet-expansion RNA-binding protein
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
  • Reactivity
    Chicken, Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203