anti-MBNL1 antibody [1H1]
ARG10721
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityChicken, Human
TargetMBNL1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-MBNL1 antibody [1H1]
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1H1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4154
- Target nameMBNL1
- Target descriptionmuscleblind like splicing regulator 1
- Target synonymsEXP; MBNL; muscleblind-like; muscleblind-like protein 1; triplet-expansion RNA-binding protein
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
- ReactivityChicken, Human
- Storage Instruction-20°C
- UNSPSC12352203