anti-MCP3 antibody [113] (HRP)

Arigo Biolaboratories

anti-MCP3 antibody [113] (HRP)

23

ELISA

Research Use Only

Monoclonal

113

HRP

CCL7

C-C motif chemokine ligand 7

C-C motif chemokine 7; chemokine (C-C motif) ligand 7; FIC; MARC; MCP3; MCP-3; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; SCYA6; SCYA7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7

Mouse

IgG1

Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78% sequence homology with MCP-1 and 58% sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1alpha to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.

Human

-20°C

12352203