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anti-MDC1 antibody [P2B11]

ARG22275
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse
TargetMdc1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-MDC1 antibody [P2B11]
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    P2B11
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID240087
  • Target name
    Mdc1
  • Target description
    mediator of DNA damage checkpoint 1
  • Target synonyms
    6820401C03; AA413496; mediation of DNA damage checkpoint 1; mediator of DNA damage checkpoint protein 1; mKIAA0170; NFBD; Nfbd1
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203