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anti-MECT1 / TORC1 antibody

Research Use Only
ARG54064
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetCRTC1
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-MECT1 / TORC1 antibody
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23373
  • Target name
    CRTC1
  • Target description
    CREB regulated transcription coactivator 1
  • Target synonyms
    CREB-regulated transcription coactivator 1; Mam-2; MAML2; Mastermind-like protein 2; MECT1; mucoepidermoid carcinoma translocated protein 1; TORC1; TORC-1; transducer of regulated cAMP response element-binding protein (CREB) 1; WAMTP1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 Ser-133 phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses (By similarity)
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203