anti-MED14 antibody

Arigo Biolaboratories

anti-MED14 antibody

23

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MED14

mediator complex subunit 14

activator-recruited cofactor 150 kDa component; ARC150; cofactor required for Sp1 transcriptional activation, subunit 2 (150kD); CRSP complex subunit 2; CRSP150; CRSP2; CSRP; CXorf4; DRIP150; EXLM1; hRGR1; human homolog of yeast RGR1; mediator of RNA polymerase II transcription subunit 14; RGR1; RGR1 homolog; thyroid hormone receptor-associated protein complex 170 kDa component; thyroid hormone receptor-associated protein complex component TRAP170; transcriptional co-activator CRSP150; TRAP170; vitamin D receptor-interacting protein complex component DRIP150; vitamin D3 receptor-interacting protein complex 150 kDa component

Rabbit

IgG

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203