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anti-MEK5 phospho (Ser311 / Thr315) antibody

Research Use Only
ARG52336
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityBovine, Canine, Chicken, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
TargetMap2k5
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-MEK5 phospho (Ser311 / Thr315) antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID29568
  • Target name
    Map2k5
  • Target description
    mitogen activated protein kinase kinase 5
  • Target synonyms
    dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPK/ERK kinase 5; MAPKK 5; MEK 5; Mek5
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation (Cameron et al., 2004).
  • Reactivity
    Bovine, Canine, Chicken, Human, Mouse, Primate, Rat, Xenopus, Zebra Fish
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203