Western blot: 35 microg of Human skin lysate (in RIPA buffer) stained with ARG64008 anti-Melanoma gp100 antibody at 1 microg/ml dilution and incubated at RT for 1 hour.
Western blot: 35 microg of Human skin lysate (in RIPA buffer) stained with ARG64008 anti-Melanoma gp100 antibody at 1 microg/ml dilution and incubated at RT for 1 hour.
anti-Melanoma gp100 antibody
ARG64008
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetPMEL
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Melanoma gp100 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID6490
- Target namePMEL
- Target descriptionpremelanosome protein
- Target synonymsD12S53E; gp100; ME20; ME20M; ME20-M; melanocyte protein mel 17; melanocyte protein PMEL; melanocyte protein Pmel 17; melanocytes lineage-specific antigen GP100; melanoma-associated ME20 antigen; melanosomal matrix protein17; P1; P100; PMEL17; SI; SIL; SILV; silver locus protein homolog; silver, mouse, homolog of
- HostGoat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203