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anti-Melanophilin antibody

Research Use Only
ARG63475
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetMlph
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Melanophilin antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID171531
  • Target name
    Mlph
  • Target description
    melanophilin
  • Target synonyms
    2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84; D1Wsu84e; exophilin-3; l(1)-3Rk; l1Rk3; leaden protein; ln; melanophilin; Sla; Slac-2a; slaC2-a; slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
  • Host
    Goat
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203