anti-Melanophilin antibody
ARG63475
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetMlph
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Melanophilin antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID171531
- Target nameMlph
- Target descriptionmelanophilin
- Target synonyms2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84; D1Wsu84e; exophilin-3; l(1)-3Rk; l1Rk3; leaden protein; ln; melanophilin; Sla; Slac-2a; slaC2-a; slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
- HostGoat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203