Anti-Methylene diphenyl diisocyanate [AH6]

Absolute Antibody

Anti-Methylene diphenyl diisocyanate [AH6]

7

The antibody binds specifically to MDI, a low-molecular weight aromatic diisocyanate which is commonly used to make polyurethane. MDI is also a major cause of occupational asthma, due to its ability to sensitize the immune system and elicit an immune response. In humans, the carrier protein albumin is able to recognise and conjugate with MID, forming a complex which is bound by IgE, triggering an asthmatic attack. Monoclonal antibodies directed against MID can be applied to diagnostics and research,and can be used to detect and quantitate MID levels in blood and urine, as well as in environmental samples. Monoclonal antibodies AD3 and AH6 bind to similar or overlapping epitopes.

Western Blot, ELISA

Research Use Only

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203