anti-MHC Class II I Ab antibody [25-9-3]
ARG21061
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityMouse
TargetH2-Ea
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-MHC Class II I Ab antibody [25-9-3]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID25-9-3
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID100504404
- Target nameH2-Ea
- Target descriptionhistocompatibility 2, class II antigen E alpha
- Target synonymsAI323765; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2E; H-2Ea; H2-Ea-ps; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; I; Ia; Ia3; Ia-3; I-E; I-E alpha MHC class II; I-Ealpha; MHC class II alpha chain; MHC class II antigen E alpha; MHC class II antigen IEk-alpha; MHC class II H2-E alpha chain; MHC class II protein; MHC-H2-Ea
- HostMouse
- IsotypeIgM
- Scientific DescriptionThis locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5 end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011]
- ReactivityMouse
- Storage Instruction-20°C
- UNSPSC12352203