anti-MICA + MICB antibody [6D4] (low endotoxin)

Arigo Biolaboratories

anti-MICA + MICB antibody [6D4] (low endotoxin)

23

Functional Assay, Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

6D4

1 mg/ml

Unconjugated

MICB

MHC class I polypeptide-related sequence B

MHC class I antigen-related protein B; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MHC class I-like molecule PERB11.2-IMX; PERB11.2; stress inducible class I homolog

Mouse

IgG2a

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Human

-20°C

12352203