Anti-MMACHC [N230/21]

Absolute Antibody

Anti-MMACHC [N230/21]

7

This antibody is specific for the MMACHC protein. MMACHC is a cobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofac

This antibody was used to preform a western blot on lysated mouse embryos (Moreno-Garcia et al, 2014; PMID:24889031).

Western Blot

WB

Research Use Only

Monoclonal

N230/21

MMACHC

metabolism of cobalamin associated C

alkylcobalamin:glutathione S-alkyltransferase; cblC; cyanocobalamin reductase (cyanide-eliminating); cyanocobalamin reductase / alkylcobalamin dealkylase; methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein

Human

IgG1

Methylmalonic aciduria and homocystinuria type C protein

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse

human, mouse

This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 1-282 (full-length) of human MMACHC.

-20°C,2°C to 8°C

12352203