Anti-Mouse CD72.1/Lyb-2.1-UNLB

Applied Biological Materials

Anti-Mouse CD72.1/Lyb-2.1-UNLB

9

Mouse CD72.1/Lyb-2.1, 45 kDa

Flow Cytometry

Research Use Only

Monoclonal

0.5 ug/ml

Unconjugated

Mouse

IgG2b

Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10-1.D.2 can itself trigger a positive signal by binding CD72.

Mouse

-20°C,2°C to 8°C

12352203