Anti-MRSA agent 18

MedChem Express

Anti-MRSA agent 18

9

Research Use Only

C36H42BrCl2N3O3

715.55

Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 microg/mL for S. aureus and 4 microg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death[1].

C=CCC1=C(C=CC(C2=C3OC(C4=C(C=CC=C4Cl)Cl)=NC3=CC(CC=C)=C2)=C1)OCCC[N+](C)(CC(NCCCC)=O)C.[Br-]

12352200