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ProductsBack/anti-Mucin-17 (human), Rabbit Monoclonal (RM517)
Immunohistochemical staining of formalin-fixed and paraffin-embedded human small intestine tissue sections using anti-Muc17 Rabbit Monoclonal Antibody (Clone RM517) at 1:100 dilution for 1 hr at room temperature.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human small intestine tissue sections using anti-Muc17 Rabbit Monoclonal Antibody (Clone RM517) at 1:100 dilution for 1 hr at room temperature.
Immunohistochemical staining of formalin-fixed and paraffin-embedded human small intestine tissue sections using anti-Muc17 Rabbit Monoclonal Antibody (Clone RM517) at 1:100 dilution for 1 hr at room temperature.

anti-Mucin-17 (human), Rabbit Monoclonal (RM517)

Research Use Only
REV-31-1409-00
RevMAb Biosciences
Product group Antibodies
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-Mucin-17 (human), Rabbit Monoclonal (RM517)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Scientific Description
    Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC-17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. MUC-17 interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. MUC-17 probably plays a role in maintaining homeostasis on mucosal surfaces. Increased expression of this molecule has been reported in colon cancer. - Recombinant Antibody. This antibody reacts to human Muc-17 (Mucin-17). Isotype: Rabbit IgG. Immunogen: A peptide corresponding to residues near the C-terminus of human Muc17. Applications: IHC. Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC-17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. MUC-17 interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. MUC-17 probably plays a role in maintaining homeostasis on mucosal surfaces. Increased expression of this molecule has been reported in colon cancer.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203