anti-Munc13-4 / UNC13D antibody

Arigo Biolaboratories

anti-Munc13-4 / UNC13D antibody

23

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

UNC13D

unc-13 homolog D

FHL3; HLH3; HPLH3; Munc13-4; protein unc-13 homolog D

Goat

IgG

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203