Anti-MVEV [M2-8E7]

Absolute Antibody

Anti-MVEV [M2-8E7]

9

This antibody reacts with domain III of the envelope protein of the Murray Valley encephalitis virus. The mAb also cross reacts with Japanese encephalitis virus.

This neutralizing antibody binds the the envelope protein of the Murray Valley encephalitis virues in the ectodomain III region. This mAb is reported to block haemagglutination. The competitive binding of the mAb to envelope protein was checked with ELISA (PMID:1703213). Recombinant MVEV E-DIII proteins were detected by M2-8E7 in a western blot assay (PMID: 29083957). This antibody is also reported to be used in immunoprecipitation for the identification of E proteins from cell lysates (PMID: 9770429, 9499070).

ImmunoPrecipitation, Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

M2-8E7

Human

IgG1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203