anti-MyD88 antibody

Arigo Biolaboratories

anti-MyD88 antibody

23

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

MYD88

MYD88 innate immune signal transduction adaptor

IMD68; mutant myeloid differentiation primary response 88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88

Goat

IgG

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Canine, Human, Mouse, Rat

-20°C

12352203