Anti-Nav1.1 Na+ channel [K74/71]

Absolute Antibody

Anti-Nav1.1 Na+ channel [K74/71]

9

This antibody is specific for Nav1.1. It does not cross-react with Nav1.2, Nav1.3 of Nav1.6.

The specificity of this antibody has been confirmed in ELISA against the GST-Nav1.1 fusion protein and immunofluorescence analysis of COS cells expressing full-length human Nav1.1 (Van Wart et al, 2005). This antibody has been used in immunoblot analysis of adult rat brain membranes, where it labels a single band at the same position as that labelled with pan-specific anti-Nav antibody K58/35 (Van Wart et al, 2005). Additionally, this antibody has been used in immunohistochemical analysis of adult rat hippocampus and whole brain sections (Van Wart et al, 2005; Andrews et al, 2019; PMID:30667360).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

K74/71

Scn1a

sodium voltage-gated channel alpha subunit 1

sodium channel protein type 1 subunit alpha; sodium channel protein type 1 subunit alpha-like; sodium channel protein type I subunit alpha; sodium channel protein, brain I subunit alpha; sodium channel, voltage-gated, type 1, alpha polypeptide; sodium channel, voltage-gated, type I, alpha polypeptide; sodium channel, voltage-gated, type I, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.1

Human

IgG1

Sodium channel protein type 1 subunit alpha

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203