anti-NDUFA1 antibody

Arigo Biolaboratories

anti-NDUFA1 antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

NDUFA1

NADH:ubiquinone oxidoreductase subunit A1

CI-MWFE; complex I MWFE subunit; MC1DN12; MWFE; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; NADH:ubiquinone oxidoreductase (complex 1); NADH-ubiquinone oxidoreductase MWFE subunit; type I dehydrogenase; ZNF183

Rabbit

IgG

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the hydrophobic protein (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203