anti-NDUFV1 antibody
ARG40141
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNDUFV1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-NDUFV1 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4723
- Target nameNDUFV1
- Target descriptionNADH:ubiquinone oxidoreductase core subunit V1
- Target synonymsCI-51K; CI51KD; complex I 51 kda subunit; complex I 51kDa subunit; complex I, mitochondrial respiratory chain; MC1DN4; mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1; mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit; NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; NADH-ubiquinone oxidoreductase 51 kDa subunit; UQOR1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinsons disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203