anti-Nephrin antibody [Y17-R]

Arigo Biolaboratories

anti-Nephrin antibody [Y17-R]

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

Y17-R

Unconjugated

NPHS1

NPHS1 adhesion molecule, nephrin

CNF; nephrin; nephrosis 1, congenital, Finnish type (nephrin); NPHN; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor; truncated NPHS1

Rabbit

IgG

This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]

Human

-20°C

12352203