Anti-Nerve growth factor (beta) [Ig 30]

Absolute Antibody

Anti-Nerve growth factor (beta) [Ig 30]

9

This antibody recognises murine and rat beta-NGF. It does not cross-react with BSA, aprotinin, EGF and insulin.

This antibody specifically recognises native beta-NGF in ELISA experiments, and denatured beta-NGF in Western blotting (Kenigsberg et al, 1991). It has also been used to detect NGF immunoreactive sites in formaldehyde-fixed tissue (Kenigsberg et al, 1991). This antibody has been shown to block the biological activity associated with NGF, including the outgrowth of NGF-induced processes from rat pheochromocytoma cells, and the increase in choline acetyltransferase activity triggered by NGF (Kenigsberg et al, 1991).

Western Blot, ELISA, ImmunoHistoChemistry, Neutralisation/Blocking

Research Use Only

Monoclonal

Ig 30

Mouse

IgG2a

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse, Rat

-20°C,2°C to 8°C

12352203