anti-Neurofilament NF-L antibody [NR-4]

Arigo Biolaboratories

anti-Neurofilament NF-L antibody [NR-4]

23

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NR-4

0.2 mg/ml

Unconjugated

NEFL

neurofilament light chain

68 kDa neurofilament protein; neurofilament light polypeptide; Neurofilament triplet L protein; neurofilament, light polypeptide; NF-L

Mouse

IgG1

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

Porcine

-20°C

12352203