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anti-Neurofilament NF-L (C-ter) antibody

ARG11140
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityRat
TargetNefl
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Neurofilament NF-L (C-ter) antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID83613
  • Target name
    Nefl
  • Target description
    neurofilament light chain
  • Target synonyms
    68 kDa neurofilament protein; 68kDa neurofilament; neurofilament light polypeptide; neurofilament triplet L protein; neurofilament, light polypeptide; NF68; Nfl; NF-L
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Reactivity
    Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203