Anti-Neutralizing Epitope [ZKA185]

Absolute Antibody

Anti-Neutralizing Epitope [ZKA185]

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This antibody is able to specifically neutralize Zika virus, however it does not react with recombinant envelope protein (E-protein) or EDIII. As a result ZKA185 has been named a Neutralizing Non-Binder (NNB) . NNBs interact with quarterny epitopes displa

This antibody, in the form of a human IgG1, has been shown to specifically neutralize Zika virus in vitro (strains tested: H/PF/2013 &MR766).

Neutralisation/Blocking

NTRL

Research Use Only

Monoclonal

ZKA185

Human

IgM

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Virus

Zika Virus

mAb ZKA185 was selected from EBV-immortalized memory B cells derived from ZIKV-infected, DENV-naïve human donors based on its ability to neutralize ZIKV infection.

-20°C,2°C to 8°C

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