anti-NKG2A + C + E antibody [20d5] (PE)

Arigo Biolaboratories

anti-NKG2A + C + E antibody [20d5] (PE)

23

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

20d5

0.1 mg/ml

RPE

Klrc1

killer cell lectin-like receptor subfamily C, member 1

CD159; CD159a; Cluster of Differentiation 159a; NKG; NKG2; NKG2A; NKG2-A/NKG2-B type II integral membrane protein; NKG2B

Rat

IgG2a

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015]

Mouse

2°C to 8°C

12352203