Anti-NKG2D [6E5A7]
Ab02029-23.0
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetKLRK1
Overview
- SupplierAbsolute Antibody
- Product NameAnti-NKG2D [6E5A7]
- Delivery Days Customer7
- Antibody SpecificityThis antibody recognizes and binds the extracellular epitope of NKG2D and blocks the interaction between ligand and receptor.
- Application Supplier NoteThe NKG2D (Natural Killer Group 2 Member D) protein is an activating receptor that enables NK and CD8 + T cells to recognize and eliminate infected or transformed endogenous cells. However, an incorrect regulation of this receptor on immune cells also appears to lead to the development of autoimmune diseases such as type I diabetes, celiac disease and RA.This antibody positively reacts with NKG2D on CD8-positive T cells and to CD56-positive natural killer cells. The binding was confirmed FACS analysis (Steigerwald, 2008).
- ApplicationsFlow Cytometry, Neutralisation/Blocking
- Applications SupplierFC; blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6E5A7
- Gene ID22914
- Target nameKLRK1
- Target descriptionkiller cell lectin like receptor K1
- Target synonymsCD314; D12S2489E; killer cell lectin-like receptor subfamily K, member 1; KLR; NK cell receptor D; NKG2D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor
- HostRabbit
- IsotypeIgG
- Protein IDP26718
- Protein NameNKG2-D type II integral membrane protein
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteThe original antibody was generated by immunizing BALB/c mice with soluble NKG2-D fragments containing amino acids from 64-462 and 123-462.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203