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Anti-NKG2D [6E5A7]

AB02029-3.0-BT
Absolute Antibody
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetKLRK1
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-NKG2D [6E5A7]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes and binds the extracellular epitope of NKG2D and blocks the interaction between ligand and receptor.
  • Application Supplier Note
    The NKG2D (Natural Killer Group 2 Member D) protein is an activating receptor that enables NK and CD8 + T cells to recognize and eliminate infected or transformed endogenous cells. However, an incorrect regulation of this receptor on immune cells also appears to lead to the development of autoimmune diseases such as type I diabetes, celiac disease and RA.This antibody positively reacts with NKG2D on CD8-positive T cells and to CD56-positive natural killer cells. The binding was confirmed FACS analysis (Steigerwald, 2008).
  • Applications
    Flow Cytometry, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    6E5A7
  • Gene ID22914
  • Target name
    KLRK1
  • Target description
    killer cell lectin like receptor K1
  • Target synonyms
    CD314; D12S2489E; killer cell lectin-like receptor subfamily K, member 1; KLR; NK cell receptor D; NKG2D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP26718
  • Protein Name
    NKG2-D type II integral membrane protein
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203