Anti-NKG2D [ADI-27749 (A49)]

Absolute Antibody

Anti-NKG2D [ADI-27749 (A49)]

7

This antibody recognizes binds human and cynomolgous monkey NKG2D with similar affinity and shows low binding affinity for mouse NKG2D. Natural killer (NK) cells serve as key innate effectors and their activity has been considered a prognostic biomarker i

This antibody is recommeded for detection of human, cynomolgous monkey and mouse NKG2D by ELISA. This antibody was capable of recognizing EL4 mouse lymphoma cell lines expressing human or mouse NKG2D-CD3 zeta signaling domain chimeric antigen receptors in a flow cytometry assay (US20210079102).

Flow Cytometry, ELISA

ELISA; FC

Research Use Only

Monoclonal

ADI-27749 (A49)

KLRK1

killer cell lectin like receptor K1

CD314; D12S2489E; killer cell lectin-like receptor subfamily K, member 1; KLR; NK cell receptor D; NKG2D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor

Mouse

IgG2b

NKG2-D type II integral membrane protein

This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab format for improved compatibility with existing reagents assays and techniques.

Human, Monkey, Mouse

Human, mouse, cynomolgous monkey

-20°C,2°C to 8°C

12352203