Anti-NKG2D [CX-5]

Absolute Antibody

Anti-NKG2D [CX-5]

7

This antibody recognizes mouse NKG2D, a lectin-like molecule expressed on both human and mouse NK cells. Mouse NKG2D binds to retinoic acid-inducible RAE-1 alpha, beta, gamma, delta, epsilon and the minor histocompatibility molecule H60 and has the abilit

It has been shown that CX5 is a non-depleting antibody, which blocks binding of NKG2D to its ligands and mediates internalization of the receptor. This antibody has been widely used to block NKG2D (Wang et al., 2018; pmid: 29447423; Yang et al., 2017; pmid: 28455530) as well as to detect NKG2D-posotive cells via flow cytometry (Hosomi et al., 2017; pmid: 28747426).

Flow Cytometry, Neutralisation/Blocking

FC, blocking, neutralizing

Research Use Only

Monoclonal

CX-5

Klrk1

killer cell lectin-like receptor subfamily K, member 1

D6H12S2489; D6H12S2489E; natural killer cell group 2D; NK cell receptor D; Nkg2; NKG2-; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor

Mouse

IgG1

NKG2-D type II integral membrane protein

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Mouse

Mouse

The original rat IgG1 version of this antibody was raised by immunizing rats against mouse KLRK1.

-20°C,2°C to 8°C

12352203