Anti-NKG2D [CX-5]

Absolute Antibody

Anti-NKG2D [CX-5]

9

This antibody recognizes mouse NKG2D, a lectin-like molecule expressed on both human and mouse NK cells. Mouse NKG2D binds to retinoic acid-inducible RAE-1 alpha, beta, gamma, delta, epsilon and the minor histocompatibility molecule H60 and has the abilit

It has been shown that CX5 is a non-depleting antibody, which blocks binding of NKG2D to its ligands and mediates internalization of the receptor. This antibody has been widely used to block NKG2D (Wang et al., 2018; pmid: 29447423; Yang et al., 2017; pmid: 28455530) as well as to detect NKG2D-posotive cells via flow cytometry (Hosomi et al., 2017; pmid: 28747426).

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

CX-5

Klrk1

killer cell lectin-like receptor subfamily K, member 1

D6H12S2489; D6H12S2489E; natural killer cell group 2D; NK cell receptor D; Nkg2; NKG2-; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor

Mouse

IgG2a

NKG2-D type II integral membrane protein

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against mouse NKG2D (Fab) and one arm directed against mouse CD3e (scFv).

Mouse

-20°C,2°C to 8°C

12352203