Anti-NKp46 [Bab281]

Absolute Antibody

Anti-NKp46 [Bab281]

7

The antibody is specific for human NKp46. The antibody cross-reacts with macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells.

The antibody was used to immunoprecipitate NKp46 molecules from NK and COS-7 cells (Pessino et al., 1998; PMID 9730896 and Cantoni et al. 1999; PMID: 10049942). NK cells were analyzed for NKp46 surface expression by immunofluorescence and Flow Cytometry analysis using the antibody (Sivori et al., 1999; PMID: 10359120). The antibody binding to NKp46 promoted an increase of cytolytic activity in NK cells (Sivori et al., 1997; PMID: 9314561 and Sivori et al., 1999; PMID: 10359120).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation

FC; IP; IF

Research Use Only

Monoclonal

Bab281

NCR1

natural cytotoxicity triggering receptor 1

CD335; LY94; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; natural killer cell p46-related protein; NK cell-activating receptor; NKP46; NK-p46

Rabbit

IgG

Natural cytotoxicity triggering receptor 1

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human, Primate

Human, Macaque

The original antibody was generated by immunizing Balb/c mice with recombinant human NKp46 protein.

-20°C,2°C to 8°C

12352203