NLRP3 is detected in mouse macrophages using anti-NLRP3/NALP3 (mouse), mAb (Cryo-1) (Prod. No AG-20B-0006). Cell extracts from mouse macrophages, WT (lane 1) or NLRP3 KO (lane 2), were separated by SDS-PAGE under reducing conditions, transferred to
NLRP3 is detected in mouse macrophages using anti-NLRP3/NALP3 (mouse), mAb (Cryo-1) (Prod. No AG-20B-0006). Cell extracts from mouse macrophages, WT (lane 1) or NLRP3 KO (lane 2), were separated by SDS-PAGE under reducing conditions, transferred to
anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)
AG-20B-0006
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetNlrp3
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-NLRP3/NALP3 (mouse), mAb (Cryo-1)
- Delivery Days Customer10
- Antibody SpecificityRecognizes mouse NLRP3/NALP3.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCryo-1
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID216799
- Target nameNlrp3
- Target descriptionNLR family, pyrin domain containing 3
- Target synonymsAGTAVPRL; AII/AVP; Ci; Cias1; cold autoinflammatory syndrome 1 protein homolog; cry; cryopyrin; FCAS; FCU; mast cell maturation-associated-inducible protein 1; Mmig; Mmig1; MWS; N; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; Pyp; Pypaf1; PYRIN-containing APAF1-like protein 1
- HostMouse
- IsotypeIgG2b
- Protein IDQ8R4B8
- Protein NameNACHT, LRR and PYD domains-containing protein 3
- Scientific DescriptionMonoclonal Antibody. Recognizes mouse NLRP3/NALP3. Isotype: Mouse IgG2b. Clone: Cryo-1. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). - The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203