Anti-Norovirus P domain [Nano-27]

Absolute Antibody

Anti-Norovirus P domain [Nano-27]

7

The binding specificity of Nano-27 for the P domain of Norovirus strain GII.10 was confirmed using ELISA (Koromyslova et al, 2017). Using ITC the Kd of Nano-27 binding to the P domain of GII.10 was estimated as 9.50x10^-9 M (Koromyslova et al, 2017). The structure of Nano-27 in complex with G11.10 P domain was also obtained (Koromyslova et al, 2017). In neutralisation assays Nano-27 did not inhibit the binding of GII.10 to A-type saliva, B-type saliva, or pig gastric mucin (Koromyslova et al, 2017).

ELISA, Neutralisation/Blocking, Other Application

ELISA; ITC; crystallography; neutralisation assay

Research Use Only

Capsid protein VP1

This chimeric rabbit antibody was made using a variable domain sequence of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

-20°C,2°C to 8°C

12352203