Bio-Connect

anti-Notch 2 antibody [HMN2-35]

ARG23293
Arigo Biolaboratories
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetNotch2
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Notch 2 antibody [HMN2-35]
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HMN2-35
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID18129
  • Target name
    Notch2
  • Target description
    notch 2
  • Target synonyms
    AI853703; Motch B; N; N2; neurogenic locus notch homolog protein 2; Notch gene homolog 2
  • Host
    Hamster
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203