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Anti-Notch 3 [hN3S2-160]

AB02408-10.0-BT
Absolute Antibody
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
TargetNOTCH3
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-Notch 3 [hN3S2-160]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody binds human notch 3.
  • Application Supplier Note
    The original human IgG1 antibody hN3S2-160 binds notch 3 with an EC50 =0.06 nM. The binding affinity of this antibody for notch 3 was determined using ELISA. The binding of hN3S2-160 to notch 3 on 293 Flp-TRex cells was done using flow cytometry. This antibody is also capable of blocking notch 3 and DLL4 ligand interaction (WO2010141249).
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    hN3S2-160
  • Gene ID4854
  • Target name
    NOTCH3
  • Target description
    notch receptor 3
  • Target synonyms
    CADASIL; CADASIL1; CASIL; IMF2; LMNS; neurogenic locus notch homolog protein 3; notch 3; Notch homolog 3
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDQ9UM47
  • Protein Name
    Neurogenic locus notch homolog protein 3
  • Scientific Description
    This full-length, reformatted human antibody was made using the variable domain sequences of the original Human scFv format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203