Anti-NS1 [ZKA25]

Absolute Antibody

Anti-NS1 [ZKA25]

9

ZKA25 reacts specifically with ZIKV NS1, shown by ELISA (Stettler et al, 2016). The mAb does not show cross-reactivity with NS1 protein from any of the four DENV serotypes.

ZKA25 was shown to react specifically with ZIKV, and not DENV1-4, NS1 protein by standard ELISA (Stettler et al, 2016). This mAb was also used in a sandwich ELISA as a serological diagnostic tool to detect viral NS1 from biological fluids obtained from patients with diagnosed ZIKV and DENV infection. This antibody can be used as a positive cotrol in the detection of Zika virus using the blockade-of-binding assays described by Balmaseda (PMID: 28716913 and 29305550) in combination with antibody ZKA35 (Ab01036-10.0-BOB).

ELISA

Research Use Only

Monoclonal

ZKA25

Mouse

IgM

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203