Bio-Connect

anti-NT-proBNP antibody [13G12]

ARG10407
Arigo Biolaboratories
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetNPPB
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-NT-proBNP antibody [13G12]
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    13G12
  • Concentration
    1.0-2.0 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4879
  • Target name
    NPPB
  • Target description
    natriuretic peptide B
  • Target synonyms
    BNP; brain natriuretic factor prohormone; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptides B; natriuretic protein; preproBNP; proBNP
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The proteins biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203