anti-NT-proBNP antibody [13G12]
ARG10407
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetNPPB
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-NT-proBNP antibody [13G12]
- Delivery Days Customer23
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID13G12
- Concentration1.0-2.0 mg/ml
- ConjugateUnconjugated
- Gene ID4879
- Target nameNPPB
- Target descriptionnatriuretic peptide B
- Target synonymsBNP; brain natriuretic factor prohormone; brain type natriuretic peptide; gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptides B; natriuretic protein; preproBNP; proBNP
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThis gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The proteins biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The presence of myocardial injury is a significant predictor of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients, and there is evidence of increased levels of natriuretic peptide B in hospitalized non-survivor COVID-19 patients. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Aug 2020]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203