anti-NTAL / LAB antibody [NAP-07] (PE)

Arigo Biolaboratories

anti-NTAL / LAB antibody [NAP-07] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

NAP-07

0.1 mg/ml

RPE

LAT2

linker for activation of T cells family member 2

HSPC046; LAB; linker for activation of B-cells; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; membrane-associated adapter molecule; non-T-cell activation linker; NTAL; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; Williams-Beuren syndrome chromosomal region 5 protein; WSCR5

Mouse

IgG1

NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

Human

2°C to 8°C

12352203