Anti-OPAL1 Alexa Fluor(r) 647

EXBIO

Anti-OPAL1 Alexa Fluor(r) 647

7

The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.

Flow cytometry: Recommended dilution: 0.5-4 microg/ml. Intracellular staining.

Flow Cytometry, Western Blot

Research Use Only

OPAL1-01

0.1 mg/ml

AlexaFluor 647

IgG2a

OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.

Human

2°C to 8°C

12352203