anti-Osteocalcin antibody [OC4-30]

Arigo Biolaboratories

anti-Osteocalcin antibody [OC4-30]

23

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

OC4-30

1 mg/ml

Unconjugated

BGLAP

bone gamma-carboxyglutamate protein

BGP; bone Gla protein; gamma-carboxyglutamic acid-containing protein; osteocalcin

Mouse

IgG2a

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]

Bovine

-20°C

12352203