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ProductsBack/Anti-osteopontin [hu1A12]

Anti-osteopontin [hu1A12]

Ab00750-10.0
Absolute Antibody
ApplicationsELISA, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
Product group Antibodies
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-osteopontin [hu1A12]
  • Delivery Days Customer
    7
  • Application Supplier Note
    hu1A12 suppreses MDA-MB-435S (highly metastatic human breast cancer cell line) cell migration (evaluated by scratch-wound healing) and also inhibits cell adhesion of MDA-MB-435S cells to human OPN. hu1A12 also inhibits the anti-apoptotic and pro-survival functions of OPN possibly through upregulating Bax, downregulating Bcl-2, and blocking the activation of NF-kappaB. hu1A12 also has been shown to suppress primary breast tumour growth in humans through in vivo studies. This antibody has also been used in ELISA, IHC and SPR studies.
  • Applications
    ELISA, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
  • Applications Supplier
    ELISA; IHC; SPR; inhibit
  • Certification
    Research Use Only
  • Protein IDP10451
  • Protein Name
    Osteopontin
  • Scientific Description
    This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203