Anti-P-selectin [PL7-6], Mouse IgG1-D265A, Fc Silenced, kappa

Absolute Antibody

Anti-P-selectin [PL7-6], Mouse IgG1-D265A, Fc Silenced, kappa

9

This antibody is specific for human P-selectin, which is expressed by activated platelets.

This antibody has been used in flow cytometric detection of thrombin-stimulated platelets (Katayama et al, 1992), and a chimeric mouse/human version of this antibody also preferentially reacts with activated platelets (Kurome et al, 1994). This could enable the detection of platelets aggregating at sites of blood vessel injury, or the delivery of clot-dissolving drugs. The specificity of this antibody for CD62 has been confirmed in western blot and ELISA (Katayama et al, 1992), and ELISA analysis based on this antibody has been used to assess P-selectin levels in plasma sample of patients post-angina (Ikeda et al, 1995).

Flow Cytometry, Western Blot, ELISA

Research Use Only

Monoclonal

PL7-6

SELP

selectin P

CD62; CD62 antigen-like family member P; CD62P; GMP140; GMP-140; granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; GRMP; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; P-selectin; selectin P (granule membrane protein 140kDa, antigen CD62)

Mouse

IgG1

P-selectin

Human

-20°C,2°C to 8°C

12352203