Anti-p63 [BU5]

Absolute Antibody

Anti-p63 [BU5]

9

This antibody is specific for human p63, a type II transmembrane protein identified in the rough endoplasmic reticulum. Surface expression of p63 is characteristic of differentiated plasma cells, due to their high secretory activity. As a result, p63 acts

This antibody has been used to detect cells expressing p63, which is characteristic of B cells, in flow cytometric analysis of B cell surface antigen expression (Exley et al, 1987), and, similarly, to assess the extent of differentiation of Daudi cells towards the plasma cell phenotype by flow cytometry (Clemens et al, 1988). In immunofluorescence assays, this antibody strongly stains plasma cells in acetone-fixed human tonsil sections, particularly in inter-follicular T-dependent areas, in and around germinal centres and in subepithelial areas (Johnson et al, 1985). This antibody also strongly stains acinar epithelial cells in thyroid sections.

Flow Cytometry, ImmunoFluorescence

Research Use Only

Monoclonal

BU5

TP63

tumor protein p63

AIS; amplified in squamous cell carcinoma; B(p51A); B(p51B); chronic ulcerative stomatitis protein; EEC3; keratinocyte transcription factor KET; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L; transformation-related protein 63; tumor protein 63; tumor protein p53-competing protein

Human

IgG1

Tumor protein 63

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203