Anti-Parathyroid hormone-related protein [2F8-10-3]

Absolute Antibody

Anti-Parathyroid hormone-related protein [2F8-10-3]

7

The original human IgG2 version of this antibody binds parathyroid hormone-related protein with a binding affinity of 0.11 nM. The binding characterization of the human IgG2 version of this antibody towards PTHrP was done using ELISA. Excess PTHrP production causes hypercalcemia, such as tumor-dependent hypercalcemia often caused by PTHrP secreted by tumor cells in large amounts. This human anti-human PTHrP antibody has had a significant suppressive and therapeutic effect on PTHrP-induced hypercalcemia in a malignant hypercalcemia associated with tumor (MAH) model mice (JP2000080100).

ELISA

ELISA; therapeutic

Research Use Only

Parathyroid hormone-related protein

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG2 format for improved compatibility with existing reagents assays and techniques.

-20°C,2°C to 8°C

12352203