Anti-Parathyroid hormone-related protein [2F8-10-3]
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AB02786-23.0-BT
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetPTHLH
Overview
- SupplierAbsolute Antibody
- Product NameAnti-Parathyroid hormone-related protein [2F8-10-3]
- Delivery Days Customer9
- Antibody SpecificityThis antibody binds human parathyroid hormone-related protein.
- Application Supplier NoteThe original human IgG2 version of this antibody binds parathyroid hormone-related protein with a binding affinity of 0.11 nM. The binding characterization of the human IgG2 version of this antibody towards PTHrP was done using ELISA. Excess PTHrP production causes hypercalcemia, such as tumor-dependent hypercalcemia often caused by PTHrP secreted by tumor cells in large amounts. This human anti-human PTHrP antibody has had a significant suppressive and therapeutic effect on PTHrP-induced hypercalcemia in a malignant hypercalcemia associated with tumor (MAH) model mice (JP2000080100).
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2F8-10-3
- Gene ID5744
- Target namePTHLH
- Target descriptionparathyroid hormone like hormone
- Target synonymsBDE2; HHM; osteostatin; parathyroid hormone-like hormone preproprotein; parathyroid hormone-like related protein; parathyroid hormone-related protein; PLP; PTHR; PTH-related protein; PTHRP; PTH-rP
- HostRabbit
- IsotypeIgG
- Protein IDP12272
- Protein NameParathyroid hormone-related protein
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG2 format for improved compatibility with existing reagents assays and techniques.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203