Anti-Parvovirus [MAbE]

Absolute Antibody

Anti-Parvovirus [MAbE]

9

This antibody recognises both canine parvovirus (CPV-a and -b), feline panleukopenia virus (FPV-a and -b), binding to antigenic site B on the capsid. It also cross-reacts with mink enteritis virus.

This antibody is able to neutralise FPV-a and -b and CPV- and -b in haemagglutination inhibition assays (Parrish & Carmichael, 1983). It has also been used in immunoprecipitation and RIA analysis (Parrish & Carmichael, 1983). A Fab derived from this antibody has also been shown, in ELISA experiments, to recognise CPV and FPV capsids (Nelson et al, 2007), and to potently neutralise CPV (Organtini et al, 2016). This Fab has also been used in cryo-electron microscopy to determine the structure of CPV (Organtini et al, 2016).

Electron Microscopy, ImmunoPrecipitation, ELISA, Neutralisation/Blocking, RadioImmunoAssay

Research Use Only

Monoclonal

MAbE

Rat

IgG2b

Virus

-20°C,2°C to 8°C

12352203